When the body becomes less sensitive to this hormone, the pancreas responds by producing increasingly larger amounts of insulin to compensate. These elevated blood levels can stimulate accelerated growth of skin cells, leading to the characteristic thickened, darkened plaques.
In other words, the skin becomes a mirror of what’s happening in the body’s metabolism. Therefore, detecting these spots early can be a valuable opportunity to act before a more serious condition develops.
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Risk factors
Several factors increase the likelihood of developing acanthosis nigricans. Among the most important are:
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Skin disorders
- Overweight or obesity : this is the factor most associated with this condition.
- Prediabetes or type 2 diabetes: alterations in glucose management are directly related.
- Family history of diabetes: genetics plays a determining role.
- Hormonal disorders: such as polycystic ovary syndrome (PCOS), which is also related
